Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	2102
interventional	1448
Observational	618
Registry	36

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug\|placebo	427
Drug	325
Other	188
Device	141
Behavioral	128
Procedure	75
Diagnostic Test	15
Biological	14
Device\|Drug	14
Device\|Other	12
Device\|Drug\|placebo	11
Behavioral\|Other	9
Dietary Supplement	9
Biological\|placebo	8
Dietary Supplement\|placebo	8
Device\|Procedure	6
Other\|placebo	6
Drug\|Other	5
Behavioral\|Drug	4
Drug\|Radiation	4
Biological\|Drug	3
Drug\|Procedure	3
Other\|Procedure	3
Radiation	3
Combination Product	2
Device\|placebo	2
Dietary Supplement\|Drug	2
Drug\|Other\|placebo	2
Behavioral\|Biological\|Diagnostic Test	1
Behavioral\|Device	1
Behavioral\|Device\|Procedure	1
Behavioral\|Dietary Supplement\|placebo	1
Behavioral\|Drug\|placebo	1
Behavioral\|Procedure	1
Combination Product\|Drug\|placebo	1
Combination Product\|placebo	1
Device\|Diagnostic Test	1
Device\|Drug\|Other	1
Device\|Drug\|Procedure	1
Device\|Other\|Radiation	1
Diagnostic Test\|Procedure	1
Dietary Supplement\|Other	1
Drug\|Genetic\|Procedure	1
Drug\|Other\|Procedure	1
Drug\|placebo\|Procedure	1
Drug\|placebo\|Radiation	1
placebo	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	346
NA	121
United Kingdom	79
Germany	71
Canada	68
China	46
France	43
Brazil	31
Spain	27
Netherlands	26
Belgium	23
Italy	22
Denmark	21
Japan	19
Norway	18
Switzerland	17
Turkey	15
United States\|Canada	13
Australia	11
Kyrgyzstan	10
Sweden	10
Israel	9
Taiwan	9
Poland	8
Austria	7
Egypt	7
India	7
Korea, Republic of	6
Thailand	6
Hong Kong	5
Portugal	5
Tunisia	5
United States\|Germany	4
United States\|Puerto Rico	4
Greece	3
Ireland	3
Netherlands\|United Kingdom	3
New Zealand	3
Singapore	3
United States\|Australia\|Canada\|New Zealand	3
United States\|Australia\|New Zealand	3
Argentina	2
Australia\|New Zealand	2
Bangladesh	2
Belgium\|Netherlands	2
Colombia	2
Germany\|Spain\|United Kingdom	2
Germany\|Switzerland	2
Hungary	2
Indonesia	2
Japan\|	2
Pakistan	2
Russian Federation	2
Saudi Arabia	2
Slovenia	2
Sweden\|United Kingdom	2
United States\|Argentina\|Belgium\|Canada\|Chile\|China\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Poland\|Russian Federation\|Spain\|United Kingdom	2
United States\|United Kingdom	2
Andorra\|Austria\|Belgium\|Bulgaria\|Czech Republic\|Denmark\|France\|Germany\|Hungary\|Italy\|Netherlands\|Poland\|Romania\|Russian Federation\|Spain\|United Kingdom	1
Argentina\|Australia\|Belgium\|Brazil\|Denmark\|Germany\|India\|Philippines\|United Kingdom	1
Argentina\|Australia\|Canada\|Chile\|Czechia\|France\|Greece\|Hungary\|Korea, Republic of\|Netherlands\|Russian Federation\|South Africa\|United Kingdom	1
Argentina\|Australia\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Romania\|Russian Federation\|Spain	1
Argentina\|Australia\|Germany\|India\|United Kingdom\|	1
Argentina\|Brazil\|Bulgaria\|Chile\|Germany\|Korea, Republic of\|Slovakia\|Spain	1
Argentina\|Brazil\|Canada\|Croatia\|Czech Republic\|Denmark\|Finland\|Germany\|Hong Kong\|India\|Italy\|Korea, Republic of\|Malaysia\|Norway\|Philippines\|South Africa\|Spain\|Sweden\|Thailand\|Ukraine	1
Argentina\|Brazil\|Canada\|Czech Republic\|Denmark\|Finland\|Germany\|Hong Kong\|India\|Italy\|Korea, Republic of\|Malaysia\|Norway\|Philippines\|Romania\|Russian Federation\|South Africa\|Spain\|Sweden\|Thailand	1
Argentina\|Chile\|China\|Taiwan	1
Argentina\|Chile\|Colombia\|Czech Republic\|Denmark\|Ecuador\|Egypt\|Estonia\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Latvia\|Lithuania\|Netherlands\|Peru\|Romania\|Russian Federation\|Slovakia\|Spain\|Switzerland\|Turkey\|United Kingdom	1
Argentina\|Chile\|Czechia\|Germany\|Hungary\|Norway\|Romania\|Russian Federation\|Spain\|Sweden	1
Argentina\|Chile\|New Zealand\|South Africa	1
Argentina\|Colombia\|Croatia\|Estonia\|Hungary\|India\|Israel\|Korea, Republic of\|Latvia\|Mexico\|Panama\|Poland\|Russian Federation\|Serbia\|Slovenia\|Turkey\|United Kingdom	1
Argentina\|Colombia\|Italy\|Malaysia\|Mexico\|Netherlands\|Spain\|Switzerland\|United Kingdom	1
Argentina\|France\|Germany\|Italy\|Norway\|Russian Federation\|Ukraine	1
Argentina\|Mexico\|Russian Federation\|Ukraine	1
Australia\|Austria\|Belgium\|Brazil\|Canada\|Denmark\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Russian Federation\|Slovakia\|South Africa\|Spain\|Turkey\|United Kingdom	1
Australia\|Austria\|Canada\|France\|Germany	1
Australia\|Austria\|Canada\|France\|Hungary\|Italy\|Netherlands\|Poland\|Portugal\|Russian Federation\|South Africa\|Spain\|Switzerland\|United Kingdom	1
Australia\|Belgium\|Brazil\|Bulgaria\|China\|Denmark\|France\|Germany\|Greece\|Hungary\|Italy\|Netherlands\|New Zealand\|Philippines\|Poland\|Russian Federation\|South Africa\|Spain\|Taiwan\|Tunisia\|Turkey\|Ukraine\|United Kingdom	1
Australia\|Belgium\|Canada\|Czechia\|Denmark\|Germany\|Greece\|Ireland\|Israel\|Italy\|Poland\|Portugal\|Spain\|United Kingdom	1
Australia\|Belgium\|Canada\|France\|Germany\|Italy\|Spain\|Turkey	1
Australia\|Bulgaria\|Germany\|Netherlands\|New Zealand\|Romania	1
Australia\|Canada	1
Australia\|Canada\|Denmark\|France\|Ireland\|Netherlands\|New Zealand\|United Kingdom	1
Australia\|Canada\|France\|Germany\|Hungary\|Poland\|Slovakia\|Spain\|Sweden	1
Australia\|Chile\|New Zealand	1
Australia\|China\|India	1
Australia\|China\|Korea, Republic of\|New Zealand\|Taiwan	1
Australia\|Czech Republic\|Poland\|Russian Federation	1
Australia\|Czechia\|Denmark\|Finland\|France\|Greece\|Hungary\|Norway\|Poland\|Portugal\|Russian Federation\|Spain	1
Australia\|Germany\|Netherlands\|New Zealand\|Poland\|South Africa\|Spain	1
Austria\|Belgium\|Bulgaria\|Croatia\|Czech Republic\|Denmark\|Finland\|France\|Germany\|Hungary\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Romania\|Russian Federation\|Slovakia\|South Africa\|Spain\|Sweden\|Ukraine\|United Kingdom	1
Austria\|Belgium\|Canada\|France\|Germany\|Italy\|Netherlands\|South Africa\|Spain\|United Kingdom	1
Austria\|Belgium\|Canada\|Germany\|Russian Federation	1
Austria\|Belgium\|Czech Republic\|Denmark\|Estonia\|Germany\|Greece\|Italy\|Latvia\|Lithuania\|Netherlands\|Norway\|Romania\|Russian Federation\|Slovakia\|Slovenia\|Spain\|Sweden\|Ukraine\|United Kingdom\|	1
Austria\|Belgium\|Denmark\|France\|Germany\|Netherlands\|South Africa\|Sweden	1
Austria\|Belgium\|France\|Germany\|Netherlands\|United Kingdom	1
Austria\|Bulgaria\|Canada\|Czech Republic\|France\|Germany\|Hungary\|Italy\|Lithuania\|Netherlands\|Poland\|South Africa\|Spain\|United Kingdom	1
Austria\|Denmark\|Netherlands\|Norway\|Sweden	1
Austria\|France	1
Austria\|France\|Germany\|Hungary\|Italy\|Spain\|United Kingdom	1
Austria\|France\|Germany\|Israel	1
Belgium\|Bulgaria\|Finland\|Germany\|Hungary\|Israel\|Poland\|Romania\|Russian Federation\|Sweden	1
Belgium\|Bulgaria\|Greece\|Hungary\|Ireland\|Russian Federation\|Slovakia\|Spain\|Turkey\|United Kingdom	1
Belgium\|Canada\|Germany\|Netherlands	1
Belgium\|Canada\|Germany\|Spain\|United Kingdom	1
Belgium\|Czech Republic\|Denmark\|Germany\|Hungary\|Netherlands\|Spain\|Sweden	1
Belgium\|Czech Republic\|Estonia\|Germany\|Hungary\|Korea, Republic of\|Lithuania\|Norway\|Spain	1
Belgium\|Denmark\|Finland\|Germany\|Netherlands	1
Belgium\|Denmark\|Germany\|Hungary	1
Belgium\|Denmark\|Netherlands\|Romania\|Russian Federation	1
Belgium\|Finland\|France\|Germany\|Italy\|Netherlands\|Spain\|Sweden\|United Kingdom	1
Belgium\|France\|Germany\|Italy\|Philippines\|Poland\|Russian Federation\|Spain\|Ukraine	1
Belgium\|France\|Germany\|Netherlands\|Portugal\|Spain	1
Belgium\|France\|Japan	1
Belgium\|Germany	1
Belgium\|Greece\|Netherlands\|Switzerland\|United Kingdom	1
Belgium\|Italy\|Netherlands	1
Belgium\|Sweden	1
Bulgaria	1
Bulgaria\|China\|Czechia\|Estonia\|Germany\|Greece\|Hungary\|Italy\|Korea, Republic of\|Mexico\|Poland\|Romania\|Russian Federation\|Slovakia\|Ukraine	1
Bulgaria\|Czech Republic\|Hungary\|Poland\|Romania\|Slovakia	1
Bulgaria\|Finland\|Germany\|Hungary\|Slovakia	1
Bulgaria\|Germany\|Hungary\|Korea, Republic of\|Latvia\|Lithuania\|Macedonia, The Former Yugoslav Republic of\|Poland\|Romania\|Russian Federation\|Slovakia\|South Africa\|Spain\|Ukraine\|United Kingdom	1
Bulgaria\|Germany\|Hungary\|Ukraine	1
Bulgaria\|Germany\|Poland\|United Kingdom	1
Bulgaria\|Japan\|Romania\|Russian Federation\|Ukraine	1
Bulgaria\|Romania\|Russian Federation	1
Bulgaria\|Slovakia	1
Canada\|Croatia\|Czech Republic\|Estonia\|France\|Germany\|Guatemala\|India\|Korea, Republic of\|Latvia\|Lithuania\|Philippines\|Poland\|South Africa\|Taiwan	1
Canada\|Denmark	1
Canada\|Denmark\|Netherlands\|Romania\|Ukraine	1
Canada\|France\|Hungary\|India\|Korea, Republic of\|Latvia\|Lithuania\|Romania\|South Africa\|United Kingdom	1
Canada\|France\|Ireland\|Italy\|Netherlands\|Russian Federation	1
Canada\|France\|Portugal\|Spain	1
Canada\|Germany\|Hungary\|Spain	1
Canada\|Germany\|Netherlands\|Sweden	1
Canada\|Germany\|Spain	1
Canada\|Netherlands\|Switzerland	1
Canada\|United States\|Australia\|Germany\|Japan\|Korea, Republic of\|Philippines\|Poland\|Russian Federation\|Slovakia\|Taiwan\|Ukraine	1
Chile	1
China\|Hong Kong\|Indonesia\|Korea, Republic of\|Thailand	1
China\|India\|Korea, Republic of\|Philippines	1
China\|Japan\|Korea, Republic of	1
China\|Korea, Republic of	1
China\|Korea, Republic of\|Philippines\|Taiwan	1
China\|Korea, Republic of\|Philippines\|Taiwan\|Thailand	1
China\|Korea, Republic of\|Taiwan	1
Colombia\|Czech Republic\|Canada\|Denmark\|Finland\|France\|Germany\|Hungary\|Iceland\|India\|Italy\|Peru\|Russian Federation\|Slovakia\|Taiwan	1
Czech Republic\|France\|Germany\|Hungary\|Italy\|Peru\|Poland\|Russian Federation\|South Africa\|Spain\|Ukraine	1
Czech Republic\|Germany\|Hungary\|Korea, Republic of\|Malaysia\|Poland\|Russian Federation\|Taiwan	1
Czech Republic\|Germany\|Hungary\|Poland	1
Czech Republic\|Poland\|United Kingdom	1
Czech Republic\|Romania	1
Czechia\|Denmark\|Germany\|Hungary\|Netherlands\|Poland\|Russian Federation\|Spain	1
Czechia\|Germany\|Greece\|Netherlands	1
Denmark\|Estonia\|Finland\|Italy\|Lithuania\|Slovakia\|Spain\|United Kingdom	1
Denmark\|Finland\|Germany\|Netherlands\|United Kingdom	1
Denmark\|Finland\|Netherlands\|Norway	1
Denmark\|Finland\|Netherlands\|Norway\|Sweden	1
Denmark\|Germany	1
Denmark\|Germany\|Poland\|Sweden\|United Kingdom	1
Denmark\|Norway\|Sweden	1
Estonia\|Finland\|Germany\|Korea, Republic of\|Latvia\|Lithuania\|Netherlands\|New Zealand\|Russian Federation\|Slovenia\|South Africa\|United Kingdom	1
Estonia\|Finland\|Germany\|Netherlands\|Russian Federation\|Slovakia	1
Estonia\|Germany	1
Finland	1
Finland\|Austria\|Denmark\|France\|Slovenia	1
Finland\|Germany\|Netherlands\|Russian Federation\|United Kingdom	1
France\|Italy	1
France\|Italy\|Spain\|Tunisia	1
France\|United States\|Belgium\|China\|Germany\|Hong Kong\|Italy\|Korea, Republic of\|Netherlands\|Singapore\|Spain\|Taiwan\|United Kingdom	1
Germany\|Greece\|Italy\|Netherlands\|Spain\|United Kingdom	1
Germany\|Hungary\|Italy	1
Germany\|Italy\|South Africa\|Switzerland	1
Germany\|Netherlands	1
Germany\|Netherlands\|United Kingdom	1
Germany\|Poland	1
Germany\|United States\|Belgium\|Hungary	1
Germany\|United States\|Bulgaria\|Japan\|Korea, Republic of\|Poland\|Romania\|Russian Federation\|South Africa\|Taiwan\|Ukraine	1
Germany\|United States\|Czech Republic\|Hungary\|India\|Slovakia\|Spain\|Turkey	1
Greece\|United States\|Finland\|Italy\|Portugal\|Sweden\|Turkey\|United Kingdom	1
Hong Kong\|India\|Japan\|Korea, Republic of\|Singapore\|Taiwan	1
Hong Kong\|Korea, Republic of\|Malaysia\|Philippines\|Taiwan	1
Iceland	1
India\|Japan\|Korea, Republic of\|Philippines\|Poland\|Russian Federation\|Taiwan\|Ukraine\|Vietnam	1
Iran, Islamic Republic of	1
Italy\|Spain\|Sweden	1
Japan\|United States\|Argentina\|Czechia\|Germany\|Poland\|Romania\|Russian Federation\|Ukraine	1
Korea, Republic of\|United States\|Australia\|Canada\|Japan\|Netherlands\|Romania\|Russian Federation\|Singapore\|Spain\|Turkey	1
Malawi\|Zimbabwe	1
Malaysia	1
Malaysia\|Singapore	1
Malta	1
Mexico	1
Netherlands\|South Africa	1
New Zealand\|Thailand\|United Kingdom	1
Norway\|Sweden	1
Peru	1
Slovakia\|Ukraine	1
South Africa	1
South Africa\|Estonia\|Germany\|Netherlands\|Romania\|Russian Federation\|Slovakia\|Sweden\|Ukraine	1
South Africa\|United Kingdom	1
Spain\|France\|Germany	1
Spain\|France\|Germany\|Italy	1
Spain\|Sweden	1
United States\|Andorra\|Argentina\|Brazil\|Chile\|France\|Germany\|Greece\|Ireland\|Israel\|Italy\|Mexico\|South Africa\|Spain\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|Chile\|China\|Croatia\|Czech Republic\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Hong Kong\|Hungary\|Iceland\|Italy\|Latvia\|Lithuania\|Malaysia\|Mexico\|Netherlands\|New Zealand\|Norway\|Pakistan\|Philippines\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Singapore\|Slovakia\|South Africa\|Spain\|Sweden\|Taiwan\|Thailand\|Ukraine\|United Kingdom\|	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|Chile\|Colombia\|Croatia\|Czechia\|Denmark\|Finland\|France\|Germany\|Greece\|Guatemala\|Hong Kong\|Hungary\|India\|Ireland\|Italy\|Japan\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Mexico\|Netherlands\|New Zealand\|Norway\|Philippines\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|Slovenia\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Colombia\|Croatia\|Denmark\|Finland\|France\|Georgia\|Germany\|Greece\|Guatemala\|Hungary\|India\|Ireland\|Israel\|Italy\|Korea, Republic of\|Latvia\|Lithuania\|Malaysia\|Mexico\|Netherlands\|New Zealand\|Norway\|Panama\|Peru\|Philippines\|Poland\|Portugal\|Puerto Rico\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Tunisia\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Chile\|China\|Colombia\|Czechia\|Denmark\|Finland\|France\|Germany\|Hong Kong\|Israel\|Japan\|Korea, Republic of\|Netherlands\|New Zealand\|Norway\|Peru\|Philippines\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Singapore\|South Africa\|Spain\|Sweden\|Thailand\|Turkey\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Chile\|China\|Czechia\|Denmark\|Finland\|France\|Germany\|Greece\|India\|Israel\|Italy\|Japan\|Malaysia\|Mexico\|Netherlands\|Norway\|Poland\|Portugal\|Spain\|Sweden\|Switzerland\|Thailand\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Czech Republic\|Denmark\|Finland\|France\|Germany\|Greece\|Hong Kong\|Hungary\|Ireland\|Italy\|Japan\|Lithuania\|Malaysia\|Mexico\|Netherlands\|New Zealand\|Norway\|Philippines\|Poland\|Portugal\|Russian Federation\|Singapore\|Slovakia\|Slovenia\|South Africa\|Spain\|Switzerland\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Canada\|Chile\|Germany\|Italy\|New Zealand	1
United States\|Argentina\|Australia\|Austria\|Brazil\|Canada\|Chile\|Colombia\|Czechia\|Denmark\|Germany\|Hungary\|Italy\|Japan\|Korea, Republic of\|Netherlands\|New Zealand\|Philippines\|Poland\|Spain\|Sweden\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Croatia\|Czechia\|Denmark\|France\|Greece\|Italy\|Korea, Republic of\|Poland\|Romania\|Spain\|Sweden\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Croatia\|Czechia\|Denmark\|France\|Greece\|Italy\|Korea, Republic of\|Poland\|Romania\|Spain\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Chile\|Colombia\|Croatia\|Denmark\|France\|Israel\|Mexico\|New Zealand\|Norway\|Peru\|Philippines\|Poland\|Serbia\|Slovenia\|Sweden\|Taiwan\|Thailand\|Turkey\|Ukraine\|Vietnam	1
United States\|Argentina\|Australia\|Bulgaria\|Canada\|Chile\|Czech Republic\|Hungary\|India\|New Zealand\|Poland\|Slovakia\|South Africa\|Sweden\|United Kingdom	1
United States\|Argentina\|Australia\|Bulgaria\|Canada\|China\|Czech Republic\|Denmark\|Estonia\|Finland\|France\|Germany\|Guatemala\|Hungary\|India\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|New Zealand\|Portugal\|Russian Federation\|Slovenia\|Turkey	1
United States\|Argentina\|Australia\|Canada\|Chile\|Denmark\|Germany\|Italy\|Mexico\|Netherlands\|Peru\|South Africa\|Spain\|Sweden\|United Kingdom	1
United States\|Argentina\|Australia\|Canada\|Chile\|Denmark\|Germany\|Japan\|Korea, Republic of\|Netherlands\|Romania\|Slovakia\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Canada\|Chile\|Estonia\|Germany\|Italy\|Mexico\|Netherlands\|Peru\|Philippines\|South Africa\|Sweden\|United Kingdom	1
United States\|Argentina\|Australia\|Canada\|Chile\|Germany\|Korea, Republic of\|Mexico\|Romania\|South Africa	1
United States\|Argentina\|Australia\|Canada\|Chile\|Germany\|Poland\|Russian Federation\|Turkey\|Ukraine	1
United States\|Argentina\|Australia\|Canada\|France\|Germany\|Italy\|Mexico\|Netherlands\|South Africa\|Spain\|Sweden	1
United States\|Argentina\|Australia\|Canada\|Mexico\|New Zealand\|South Africa	1
United States\|Argentina\|Australia\|Colombia\|Denmark\|Germany\|Guatemala\|Mexico\|Philippines\|South Africa\|Spain\|Turkey	1
United States\|Argentina\|Austria\|Belgium\|Brazil\|Canada\|Chile\|Denmark\|Germany\|Italy\|Mexico\|Norway\|Peru\|Puerto Rico\|Russian Federation\|South Africa\|Spain\|Sweden\|United Kingdom	1
United States\|Argentina\|Austria\|Canada\|Colombia\|Czech Republic\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Hungary\|India\|Ireland\|Israel\|Italy\|Mexico\|Netherlands\|Peru\|Philippines\|Poland\|Puerto Rico\|Russian Federation\|Slovakia\|South Africa\|Spain\|United Kingdom	1
United States\|Argentina\|Austria\|Canada\|Germany\|Netherlands\|Russian Federation\|Sweden	1
United States\|Argentina\|Belgium\|Canada\|Czechia\|Germany\|Italy\|Netherlands\|Poland	1
United States\|Argentina\|Brazil\|Chile\|Costa Rica\|Mexico	1
United States\|Argentina\|Bulgaria\|Canada\|Chile\|China\|Czechia\|Denmark\|Finland\|Germany\|Hungary\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Romania\|Russian Federation\|Slovakia\|Spain\|Sweden\|Turkey\|Ukraine	1
United States\|Argentina\|Bulgaria\|Canada\|Chile\|Germany\|Hungary\|Korea, Republic of\|Netherlands\|Philippines\|Romania\|South Africa\|Thailand\|United Kingdom	1
United States\|Argentina\|Bulgaria\|Canada\|Czech Republic\|Germany\|Hungary\|Japan\|Poland\|Slovakia\|South Africa\|Spain\|Sweden\|Taiwan	1
United States\|Argentina\|Bulgaria\|Canada\|Denmark\|Hungary\|Mexico\|Poland\|Russian Federation	1
United States\|Argentina\|Bulgaria\|Canada\|Germany\|Hungary\|Romania\|Russian Federation\|Spain	1
United States\|Argentina\|Bulgaria\|Croatia\|Czechia\|Germany\|Hungary\|Poland\|Slovakia\|South Africa\|Spain\|Turkey	1
United States\|Argentina\|Canada\|Chile\|Colombia\|Italy\|Malaysia\|Mexico\|Peru\|Philippines\|Romania\|Russian Federation\|Serbia\|Spain\|Taiwan\|Thailand\|Ukraine	1
United States\|Argentina\|Canada\|Chile\|Denmark\|Estonia\|Germany\|Korea, Republic of\|Mexico\|Peru\|Philippines\|Poland\|Russian Federation\|Slovakia	1
United States\|Argentina\|Canada\|Chile\|Denmark\|France\|Germany\|Italy\|Korea, Republic of\|Romania\|Russian Federation\|South Africa\|Ukraine	1
United States\|Argentina\|Canada\|Chile\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|New Zealand\|Peru\|Poland\|Russian Federation	1
United States\|Argentina\|Canada\|Chile\|Romania	1
United States\|Argentina\|Canada\|Colombia\|Mexico\|Peru	1
United States\|Argentina\|Canada\|Finland\|France\|Germany\|Hungary\|Italy\|Spain\|United Kingdom	1
United States\|Argentina\|Canada\|Germany\|India\|Italy\|Korea, Republic of\|Puerto Rico\|Spain\|Sweden\|Taiwan\|Turkey	1
United States\|Argentina\|Chile\|Greece\|Peru\|Romania\|Ukraine	1
United States\|Argentina\|Chile\|Guatemala\|Honduras\|Romania	1
United States\|Argentina\|Chile\|Netherlands\|Peru\|South Africa	1
United States\|Argentina\|Czechia\|Estonia\|Germany\|Korea, Republic of\|Norway\|Ukraine	1
United States\|Argentina\|France\|Greece\|Korea, Republic of\|New Zealand\|Poland\|Russian Federation\|South Africa\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Germany\|Russian Federation\|Ukraine	1
United States\|Argentina\|Norway	1
United States\|Australia\|Austria\|Belgium\|Canada\|Denmark\|Germany\|New Zealand\|Poland\|Portugal\|United Kingdom	1
United States\|Australia\|Austria\|Brazil\|France\|Germany\|Hungary\|New Zealand\|Romania\|Russian Federation\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|Finland\|France\|Greece\|Ireland\|Italy\|Netherlands\|New Zealand\|Russian Federation\|South Africa\|Spain\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|Germany\|Greece\|New Zealand\|Norway\|Slovakia\|South Africa\|Sweden	1
United States\|Australia\|Belgium\|Canada\|Czechia\|Estonia\|France\|Greece\|Italy\|Mexico\|Norway\|Peru\|Poland\|Russian Federation\|Spain\|Sweden	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Greece\|Netherlands\|Norway\|Russian Federation\|Spain\|Sweden\|Turkey\|United Kingdom	1
United States\|Australia\|Brazil\|Canada\|Colombia\|Germany\|Greece\|Romania\|Russian Federation\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Bulgaria\|Canada\|France\|Germany\|Guatemala\|Hungary\|Japan\|Philippines\|Poland\|Russian Federation\|Slovakia\|South Africa\|Spain\|Switzerland\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Canada	1
United States\|Australia\|Canada\|Germany\|Korea, Republic of\|Netherlands\|Poland\|Romania\|Spain	1
United States\|Australia\|Canada\|United Kingdom	1
United States\|Australia\|China\|Germany\|New Zealand\|Taiwan	1
United States\|Australia\|New Zealand\|Poland\|Thailand	1
United States\|Austria\|Belgium\|Brazil\|Canada\|China\|Colombia\|Croatia\|Germany\|Hungary\|India\|Ireland\|Japan\|Norway\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Sweden\|Taiwan\|Turkey\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|Colombia\|Denmark\|Finland\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Mexico\|Norway\|Poland\|Russian Federation\|Slovakia\|Spain\|Switzerland\|Turkey\|United Kingdom	1
United States\|Austria\|Belgium\|Netherlands\|Switzerland\|United Kingdom	1
United States\|Austria\|Canada\|Czechia\|Germany\|Hungary\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Romania\|Russian Federation\|South Africa\|Spain\|Switzerland\|United Kingdom	1
United States\|Austria\|Netherlands\|United Kingdom	1
United States\|Belgium\|Canada\|Czech Republic\|Denmark\|Finland\|Germany\|South Africa\|Spain\|United Kingdom	1
United States\|Belgium\|Canada\|Czech Republic\|Germany\|Greece\|Netherlands\|Portugal\|Ukraine\|United Kingdom	1
United States\|Belgium\|Canada\|Czechia\|Germany\|Hungary\|Netherlands\|Poland\|Romania\|Russian Federation\|United Kingdom	1
United States\|Belgium\|Canada\|Denmark\|Germany\|Hungary\|Netherlands	1
United States\|Belgium\|Canada\|Denmark\|Italy\|Spain	1
United States\|Belgium\|Canada\|Germany	1
United States\|Belgium\|Canada\|Germany\|Netherlands	1
United States\|Belgium\|Denmark\|Estonia\|France\|Germany\|Hungary\|Japan\|Netherlands\|Norway\|Philippines\|Slovakia\|Sweden\|Ukraine	1
United States\|Belgium\|Germany\|Hungary\|Netherlands\|Poland\|Spain	1
United States\|Belgium\|Netherlands	1
United States\|Belgium\|New Zealand	1
United States\|Belgium\|Spain	1
United States\|Bulgaria\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Bosnia and Herzegovina\|Canada\|Chile\|China\|Colombia\|Croatia\|Czechia\|France\|Georgia\|Germany\|Greece\|Hungary\|India\|Indonesia\|Israel\|Italy\|Japan\|Korea, Republic of\|Latvia\|Macedonia, The Former Yugoslav Republic of\|Malaysia\|Mexico\|Netherlands\|Philippines\|Poland\|Romania\|Russian Federation\|Serbia\|Slovakia\|South Africa\|Spain\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Bulgaria\|Canada\|Chile\|Czechia\|Greece\|Japan\|Mexico\|Poland\|Russian Federation\|South Africa\|Spain\|Thailand	1
United States\|Bulgaria\|Canada\|France\|Hungary\|Russian Federation\|Ukraine	1
United States\|Bulgaria\|Czech Republic\|Hungary\|Latvia\|Lithuania\|Philippines\|Poland\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|Czechia\|Germany\|Hungary\|Israel\|Poland\|Spain\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|Czechia\|Germany\|Hungary\|Italy\|Latvia\|Poland\|Romania\|Russian Federation	1
United States\|Bulgaria\|Estonia\|Germany\|Russian Federation\|United Kingdom	1
United States\|Bulgaria\|Germany\|Hungary\|Romania\|Russian Federation\|Ukraine	1
United States\|Canada\|Colombia\|Czech Republic\|Hungary\|India\|Netherlands\|Slovakia\|Spain	1
United States\|Canada\|Czechia\|Denmark\|South Africa\|Ukraine\|United Kingdom	1
United States\|Canada\|Czechia\|Germany\|Hungary\|Korea, Republic of\|Poland\|Russian Federation	1
United States\|Canada\|Czechia\|Germany\|Poland\|Romania	1
United States\|Canada\|Denmark\|France\|Germany\|Israel\|Korea, Republic of\|Netherlands\|Spain\|United Kingdom	1
United States\|Canada\|Denmark\|France\|Germany\|Netherlands\|Romania\|United Kingdom	1
United States\|Canada\|Denmark\|Germany\|Poland\|Spain\|United Kingdom	1
United States\|Canada\|Denmark\|Germany\|United Kingdom	1
United States\|Canada\|France\|Germany\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Sweden\|Switzerland\|United Kingdom	1
United States\|Canada\|France\|Germany\|Poland\|South Africa	1
United States\|Canada\|France\|Poland\|South Africa\|Spain\|United Kingdom	1
United States\|Canada\|Germany	1
United States\|Canada\|Germany\|Hungary\|Korea, Republic of\|Mexico\|Poland\|Russian Federation\|Spain\|Taiwan	1
United States\|Canada\|Germany\|India\|Italy\|Poland\|South Africa\|Spain	1
United States\|Canada\|Germany\|Netherlands\|Spain	1
United States\|Canada\|Italy	1
United States\|Chile\|Estonia\|Germany\|Japan\|Korea, Republic of\|Mexico\|Philippines\|Poland\|Russian Federation	1
United States\|Chile\|Estonia\|Russian Federation	1
United States\|Chile\|Mexico\|Norway\|Romania\|Russian Federation\|South Africa	1
United States\|Chile\|Romania\|Russian Federation\|Slovakia\|South Africa	1
United States\|China\|Germany\|Taiwan	1
United States\|Czech Republic\|Germany\|Korea, Republic of	1
United States\|Czech Republic\|Germany\|Poland\|Romania\|South Africa	1
United States\|Czechia\|Germany	1
United States\|Czechia\|Germany\|Netherlands	1
United States\|Czechia\|Germany\|Poland\|Romania\|Russian Federation	1
United States\|Czechia\|Hungary\|Russian Federation	1
United States\|Finland\|Israel\|Italy\|Japan\|Korea, Republic of\|Portugal\|Spain\|Sweden\|United Kingdom	1
United States\|France\|Germany\|Italy\|Mexico\|Peru\|Poland\|Romania\|Russian Federation\|Ukraine	1
United States\|France\|Germany\|Netherlands\|Spain\|Turkey	1
United States\|Germany\|Italy\|Romania\|United Kingdom	1
United States\|Germany\|Italy\|South Africa\|Spain\|Ukraine	1
United States\|Germany\|Japan	1
United States\|Germany\|Korea, Republic of\|Norway\|Philippines\|Thailand	1
United States\|Germany\|Netherlands\|Norway	1
United States\|Germany\|Romania\|Russian Federation\|Ukraine	1
United States\|Germany\|South Africa	1
United States\|Germany\|Spain\|United Kingdom	1
United States\|Honduras	1
United States\|Netherlands\|United Kingdom	1
United States\|Poland\|Russian Federation	1

Sites per Study

Site_count	Study_Count
1	820
2	98
3	30
4	26
5	30
6	24
7	10
8	14
9	11
10	12
11	10
12	8
13	8
14	13
15	7
16	4
17	9
18	7
19	11
20	11
21	6
22	4
23	3
24	4
25	3
26	4
27	9
28	3
29	6
30	3
31	7
32	6
33	3
34	4
35	5
36	2
37	6
38	1
39	4
40	6
41	2
42	2
43	5
44	3
45	5
46	1
47	1
48	3
49	4
50	4
51	4
52	3
53	4
54	7
55	3
56	2
57	3
58	1
59	2
60	5
61	1
62	2
64	2
65	1
66	3
67	1
68	1
69	1
70	1
71	1
72	3
73	2
74	1
75	1
76	1
77	1
78	3
79	1
80	1
81	1
83	2
86	1
88	1
90	2
91	1
92	1
93	3
94	4
96	1
97	4
98	1
99	1
100	2
103	2
105	1
106	2
107	1
110	1
112	2
113	1
115	1
116	2
118	1
119	1
120	3
121	1
125	1
126	1
127	1
130	1
132	3
134	1
137	1
138	1
139	1
140	1
143	1
144	1
149	1
153	1
157	1
160	2
163	1
165	1
166	2
170	1
176	1
177	1
178	2
179	1
180	2
183	2
188	1
197	1
208	1
212	1
213	1
222	2
238	1
239	1
240	1
247	1
248	1
260	1
270	1
282	1
287	1
338	1
345	2
356	1
409	1
459	1
490	1
818	1
999	1
1191	1
1621	1

Phase

Phase	Study_Count
N/A	544
Phase 3	337
Phase 2	235
Phase 4	192
Phase 1	80
Phase 2/Phase 3	25
Phase 1/Phase 2	23
Early Phase 1	12

Number of Arms

Number_of_Arms	Count_of_Studies
1	198
2	785
3	144
4	80
5	44
6	25
7	7
8	10
9	3
10	2
12	3
16	1
NA	146

Number of Updates

Count of Versions	Count of Studies
1	138
2	161
3	180
4	151
5	125
6	110
7	71
8	78
9	61
10	40
11	33
12	29
13	26
14	16
15	18
16	10
17	14
18	13
19	9
20	11
21	10
22	5
23	10
24	8
25	8
26	9
27	4
28	2
29	3
30	3
31	6
32	4
33	4
34	2
35	4
36	1
37	4
38	4
39	3
40	1
41	1
43	1
44	3
45	6
48	2
49	4
50	2
52	1
53	2
54	2
55	4
56	4
57	1
58	1
59	3
61	2
64	1
67	1
72	1
73	1
74	1
81	1
82	1
88	2
89	1
92	1
94	1
100	1
103	1
114	1
142	1
145	1
150	1
158	1
161	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	12683	1310	9.681679
Contacts/Locations	6312	1134	5.566138
Recruitment Status	2092	1123	1.862867
Study Design	1630	1009	1.615461
None (earliest Version on record)	1448	1448	1.000000
Outcome Measures	1365	771	1.770428
Study Identification	958	562	1.704626
Arms	911	585	1.557265
Interventions	911	585	1.557265
Eligibility	883	491	1.798371
Sponsor/Collaborators	847	568	1.491197
Study Description	797	503	1.584493
More Information	616	235	2.621277
Oversight	540	434	1.244240
References	425	311	1.366559
Conditions	381	239	1.594142
Results	356	356	1.000000
Baseline Characteristics	262	159	1.647799
IPDSharing	219	202	1.084158
Participant Flow	117	108	1.083333
Reported Adverse Events	117	102	1.147059
Results Submission Events	94	94	1.000000
Documents	61	59	1.033898
2020 Study Status	3	3	1.000000
2020 Documents	1	1	1.000000
2020 Outcome Measures	1	1	1.000000
Quality Control Review has not concludedReturned: April 17	1	1	1.000000
Quality Control Review has not concludedReturned: April 7	1	1	1.000000
Quality Control Review has not concludedReturned: February 20	1	1	1.000000
Quality Control Review has not concludedReturned: March 31	1	1	1.000000
Quality Control Review has not concludedReturned: March 9	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	5.00000	3.00	5.00000	6.00000	1.0000	20.00	14.0000	4.0000
1st Qu.	11.50000	29.25	15.00000	24.00000	38.5000	51.00	150.0000	48.7500
Median	20.00000	60.00	25.00000	35.00000	74.0000	120.00	429.0000	125.0000
Mean	78.41667	187832.98	39.31646	70.95652	157.4217	263.44	808.3292	286.0573
3rd Qu.	58.00000	121.75	45.50000	70.50000	185.5000	243.00	902.5000	279.2500
Max.	341.00000	99999999.00	198.00000	527.00000	2080.0000	2059.00	17183.0000	2696.0000

Trial Group Type

group_type	Group_Count
Experimental	1664
Active Comparator	655
Placebo Comparator	444
No Intervention	163
Other	160
NA	146
Sham Comparator	32

Intervention Model

intervention_model	Study_Count
Parallel Assignment	882
Crossover Assignment	286
Single Group Assignment	229
NA	32
Factorial Assignment	13
Sequential Assignment	6

Primary Purpose

primary_purpose	Study_Count
Treatment	1009
Supportive Care	98
Prevention	79
Diagnostic	70
Basic Science	59
Other	59
Health Services Research	34
NA	28
Screening	7
Device Feasibility	3
Educational/Counseling/Training	2

Observational Studies

Studies by Country

Country	Study_Count
NA	198
United States	121
Germany	36
France	27
United Kingdom	26
Canada	19
China	18
Belgium	10
Italy	10
Spain	10
Korea, Republic of	9
Sweden	9
Norway	8
Switzerland	8
Taiwan	8
Japan	7
Netherlands	7
Brazil	6
Greece	6
Israel	6
Turkey	6
Denmark	5
Ireland	4
Singapore	4
Austria	3
United States\|Canada	3
Costa Rica	2
Egypt	2
Hong Kong	2
Qatar	2
Russian Federation	2
Argentina\|Bangladesh\|Brazil\|Canada\|Chile\|China\|Colombia\|India\|Iran, Islamic Republic of\|Kazakhstan\|Kyrgyzstan\|Malaysia\|Pakistan\|Palestinian Territory, occupied\|Peru\|Philippines\|Poland\|Russian Federation\|Saudi Arabia\|South Africa\|Sweden\|Tanzania\|Turkey\|United Arab Emirates\|Zimbabwe	1
Argentina\|Colombia\|Uruguay\|Venezuela	1
Australia	1
Australia\|China\|Korea, Republic of\|Taiwan	1
Australia\|Germany	1
Australia\|New Zealand\|United Kingdom	1
Australia\|United States\|Argentina\|Brazil\|Canada\|China\|Colombia\|Denmark\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Norway\|Spain\|Sweden\|United Kingdom	1
Austria\|Belgium\|Denmark\|Finland\|France\|Germany\|Greece\|Ireland\|Italy\|Netherlands\|Norway\|Portugal\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
Austria\|Czechia\|Hungary\|Israel\|Romania\|Russian Federation\|Slovakia\|Slovenia\|Switzerland	1
Austria\|Germany	1
Belgium\|Denmark\|Finland\|Germany\|Netherlands\|Norway	1
Belgium\|France\|Germany\|Netherlands\|Poland\|Spain	1
Belgium\|Greece\|Netherlands\|United Kingdom	1
Bulgaria	1
Bulgaria\|Czechia\|Hungary\|Israel\|Lithuania\|Poland\|Romania\|Russian Federation\|Slovenia\|Switzerland\|Ukraine	1
Canada\|France	1
Croatia	1
Czechia	1
Denmark\|France\|Germany	1
Egypt\|Germany\|India\|Sri Lanka	1
Germany\|India\|Sri Lanka	1
Hungary\|Slovakia\|Slovenia	1
India	1
Kazakhstan	1
Kyrgyzstan	1
Netherlands\|United Kingdom	1
Spain\|Croatia\|Denmark\|Ireland\|Italy\|Netherlands\|Norway\|Portugal\|Sweden\|United Kingdom	1
Thailand	1
United States\|Australia	1
United States\|Belgium\|Canada\|Denmark\|Finland\|Germany\|Japan\|Korea, Republic of\|Poland\|Spain\|Sweden\|United Kingdom	1
United States\|Bulgaria\|Canada\|Czech Republic\|Denmark\|Netherlands\|New Zealand\|Norway\|Slovenia\|Spain\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|Canada\|Czech Republic\|France\|Germany\|Italy\|Russian Federation\|Sweden	1
United States\|Germany\|Italy	1
United States\|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	501
2	32
3	9
4	8
5	5
6	3
7	1
8	4
9	3
10	1
12	1
13	1
14	1
15	3
16	2
17	1
18	1
19	4
20	4
21	1
22	1
23	1
26	3
32	1
34	1
40	1
41	1
42	1
44	1
47	2
51	1
57	1
60	1
79	1
90	1
108	1
123	1
141	1
169	1
177	1
185	1
188	1
233	1
298	1
352	1
388	1
418	1
605	1
606	1

Number of Updates

Count of Versions	Count of Studies
1	84
2	105
3	146
4	92
5	39
6	34
7	14
8	15
9	12
10	8
11	5
12	8
13	5
14	4
15	5
16	6
17	1
18	2
19	2
20	3
21	6
22	3
23	1
26	2
27	1
29	1
30	1
32	1
36	1
38	1
39	1
43	1
49	1
56	1
68	1
83	1
95	1
103	1
119	1
141	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	3132	534	5.865169
Contacts/Locations	1058	333	3.177177
None (earliest Version on record)	618	618	1.000000
Study Design	578	365	1.583562
Recruitment Status	518	353	1.467422
Study Description	515	226	2.278761
Study Identification	427	260	1.642308
Eligibility	362	255	1.419608
Sponsor/Collaborators	284	201	1.412935
Outcome Measures	230	149	1.543624
Oversight	182	141	1.290780
References	161	98	1.642857
Groups	109	88	1.238636
Interventions	109	88	1.238636
Conditions	84	58	1.448276
More Information	64	17	3.764706
IPDSharing	40	39	1.025641
Results	28	28	1.000000
Documents	16	14	1.142857
Baseline Characteristics	15	12	1.250000
Reported Adverse Events	7	6	1.166667
Participant Flow	4	4	1.000000
Results Submission Events	4	4	1.000000

Enrollment Metrics

Measure	Observational
Min	1.00
1st Qu	76.00
Median	214.50
Mean	420512.80
3rd Qu	897.75
Max	99999999.00

Observation Model

observational_model	Study_Count
Cohort	293
NA	151
Case-Only	57
Case-Control	36
Other	31
Case Control	30
Family-Based	6
Case-Crossover	5
Natural History	4
Defined Population, Natural History	3
Ecologic or Community	2

Time Perspective

time_perspective	Study_Count
Prospective	325
NA	131
Cross-Sectional	77
Retrospective	72
Other	8
Cross-Sectional, Prospective	2
Longitudinal	1
Longitudinal, Prospective	1
Longitudinal, Retrospective	1

Registries

Studies by Country

Country	Study_Count
United States	6
China	3
Germany	3
Korea, Republic of	3
Brazil	2
Turkey	2
United Kingdom	2
Austria	1
Austria\|Bulgaria\|Croatia\|Czech Republic\|Hungary\|Latvia\|Poland\|Russian Federation\|Serbia\|Slovakia\|Slovenia	1
Austria\|France\|Germany\|Italy\|United Kingdom	1
Belgium	1
Canada	1
Finland	1
France	1
France\|Germany\|Italy\|Turkey\|United Kingdom	1
NA	1
Netherlands	1
Poland	1
Russian Federation	1
Taiwan	1
Tunisia	1
United States\|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	27
3	2
4	1
5	1
7	1
42	1
47	1
81	1
180	1

Number of Updates

Count of Versions	Count of Studies
1	10
2	5
3	6
4	10
5	2
14	1
22	1
23	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	111	26	4.269231
Contacts/Locations	64	20	3.200000
None (earliest Version on record)	36	36	1.000000
Recruitment Status	26	15	1.733333
Study Design	24	14	1.714286
Outcome Measures	15	11	1.363636
Study Description	15	8	1.875000
References	13	4	3.250000
Eligibility	11	5	2.200000
Study Identification	11	6	1.833333
Conditions	10	4	2.500000
Oversight	10	8	1.250000
Sponsor/Collaborators	10	6	1.666667
Groups	4	2	2.000000
Interventions	4	2	2.000000
IPDSharing	2	2	1.000000
Documents	1	1	1.000000

Enrollment Metrics

Measure	Registries
Min	20.00
1st Qu	100.00
Median	475.00
Mean	3082.25
3rd Qu	2000.00
Max	75000.00

Registry Model

observational_model	Study_Count
Cohort	26
Case-Only	5
Other	3
Case-Control	2

Time Perspective

time_perspective	Study_Count
Prospective	27
Cross-Sectional	5
Other	4

Follow-up

target_duration	Study_Count
1 Day	5
1 Year	5
10 Years	5
5 Years	5
1 Month	2
12 Months	2
15 Years	2
3 Years	2
4 Years	2
2 Days	1
4 Weeks	1
6 Months	1
60 Months	1
7 Months	1
8 Years	1

intervention_type	Study_Count
Drug\|placebo	427
Drug	325
Other	188
Device	141
Behavioral	128
Procedure	75
Diagnostic Test	15
Biological	14
Device\|Drug	14
Device\|Other	12
Device\|Drug\|placebo	11
Behavioral\|Other	9
Dietary Supplement	9
Biological\|placebo	8
Dietary Supplement\|placebo	8
Device\|Procedure	6
Other\|placebo	6
Drug\|Other	5
Behavioral\|Drug	4
Drug\|Radiation	4
Biological\|Drug	3
Drug\|Procedure	3
Other\|Procedure	3
Radiation	3
Combination Product	2
Device\|placebo	2
Dietary Supplement\|Drug	2
Drug\|Other\|placebo	2
Behavioral\|Biological\|Diagnostic Test	1
Behavioral\|Device	1
Behavioral\|Device\|Procedure	1
Behavioral\|Dietary Supplement\|placebo	1
Behavioral\|Drug\|placebo	1
Behavioral\|Procedure	1
Combination Product\|Drug\|placebo	1
Combination Product\|placebo	1
Device\|Diagnostic Test	1
Device\|Drug\|Other	1
Device\|Drug\|Procedure	1
Device\|Other\|Radiation	1
Diagnostic Test\|Procedure	1
Dietary Supplement\|Other	1
Drug\|Genetic\|Procedure	1
Drug\|Other\|Procedure	1
Drug\|placebo\|Procedure	1
Drug\|placebo\|Radiation	1
placebo	1

Count of Versions	Count of Studies
1	138
2	161
3	180
4	151
5	125
6	110
7	71
8	78
9	61
10	40
11	33
12	29
13	26
14	16
15	18
16	10
17	14
18	13
19	9
20	11
21	10
22	5
23	10
24	8
25	8
26	9
27	4
28	2
29	3
30	3
31	6
32	4
33	4
34	2
35	4
36	1
37	4
38	4
39	3
40	1
41	1
43	1
44	3
45	6
48	2
49	4
50	2
52	1
53	2
54	2
55	4
56	4
57	1
58	1
59	3
61	2
64	1
67	1
72	1
73	1
74	1
81	1
82	1
88	2
89	1
92	1
94	1
100	1
103	1
114	1
142	1
145	1
150	1
158	1
161	1

Site_count	Study_Count
1	501
2	32
3	9
4	8
5	5
6	3
7	1
8	4
9	3
10	1
12	1
13	1
14	1
15	3
16	2
17	1
18	1
19	4
20	4
21	1
22	1
23	1
26	3
32	1
34	1
40	1
41	1
42	1
44	1
47	2
51	1
57	1
60	1
79	1
90	1
108	1
123	1
141	1
169	1
177	1
185	1
188	1
233	1
298	1
352	1
388	1
418	1
605	1
606	1

Count of Versions	Count of Studies
1	84
2	105
3	146
4	92
5	39
6	34
7	14
8	15
9	12
10	8
11	5
12	8
13	5
14	4
15	5
16	6
17	1
18	2
19	2
20	3
21	6
22	3
23	1
26	2
27	1
29	1
30	1
32	1
36	1
38	1
39	1
43	1
49	1
56	1
68	1
83	1
95	1
103	1
119	1
141	1

Count of Versions	Count of Studies
1	138
2	161
3	180
4	151
5	125
6	110
7	71
8	78
9	61
10	40
11	33
12	29
13	26
14	16
15	18
16	10
17	14
18	13
19	9
20	11
21	10
22	5
23	10
24	8
25	8
26	9
27	4
28	2
29	3
30	3
31	6
32	4
33	4
34	2
35	4
36	1
37	4
38	4
39	3
40	1
41	1
43	1
44	3
45	6
48	2
49	4
50	2
52	1
53	2
54	2
55	4
56	4
57	1
58	1
59	3
61	2
64	1
67	1
72	1
73	1
74	1
81	1
82	1
88	2
89	1
92	1
94	1
100	1
103	1
114	1
142	1
145	1
150	1
158	1
161	1

Site_count	Study_Count
1	501
2	32
3	9
4	8
5	5
6	3
7	1
8	4
9	3
10	1
12	1
13	1
14	1
15	3
16	2
17	1
18	1
19	4
20	4
21	1
22	1
23	1
26	3
32	1
34	1
40	1
41	1
42	1
44	1
47	2
51	1
57	1
60	1
79	1
90	1
108	1
123	1
141	1
169	1
177	1
185	1
188	1
233	1
298	1
352	1
388	1
418	1
605	1
606	1

Count of Versions	Count of Studies
1	84
2	105
3	146
4	92
5	39
6	34
7	14
8	15
9	12
10	8
11	5
12	8
13	5
14	4
15	5
16	6
17	1
18	2
19	2
20	3
21	6
22	3
23	1
26	2
27	1
29	1
30	1
32	1
36	1
38	1
39	1
43	1
49	1
56	1
68	1
83	1
95	1
103	1
119	1
141	1

lung diseases

Study Counts

Studies over Time

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Number of Updates

Update History Change Type

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Count of Versions	Count of Studies
1	138
2	161
3	180
4	151
5	125
6	110
7	71
8	78
9	61
10	40
11	33
12	29
13	26
14	16
15	18
16	10
17	14
18	13
19	9
20	11
21	10
22	5
23	10
24	8
25	8
26	9
27	4
28	2
29	3
30	3
31	6
32	4
33	4
34	2
35	4
36	1
37	4
38	4
39	3
40	1
41	1
43	1
44	3
45	6
48	2
49	4
50	2
52	1
53	2
54	2
55	4
56	4
57	1
58	1
59	3
61	2
64	1
67	1
72	1
73	1
74	1
81	1
82	1
88	2
89	1
92	1
94	1
100	1
103	1
114	1
142	1
145	1
150	1
158	1
161	1

Site_count	Study_Count
1	501
2	32
3	9
4	8
5	5
6	3
7	1
8	4
9	3
10	1
12	1
13	1
14	1
15	3
16	2
17	1
18	1
19	4
20	4
21	1
22	1
23	1
26	3
32	1
34	1
40	1
41	1
42	1
44	1
47	2
51	1
57	1
60	1
79	1
90	1
108	1
123	1
141	1
169	1
177	1
185	1
188	1
233	1
298	1
352	1
388	1
418	1
605	1
606	1

Count of Versions	Count of Studies
1	84
2	105
3	146
4	92
5	39
6	34
7	14
8	15
9	12
10	8
11	5
12	8
13	5
14	4
15	5
16	6
17	1
18	2
19	2
20	3
21	6
22	3
23	1
26	2
27	1
29	1
30	1
32	1
36	1
38	1
39	1
43	1
49	1
56	1
68	1
83	1
95	1
103	1
119	1
141	1